Antimicrobial Drug Resistance: Clinical and Epidemiological - download pdf or read online
By Lesley McGee, Keith P. Klugman (auth.), Douglas L. Mayers MD (eds.)
The volumes incorporated in Antimicrobial Drug Resistance characterize the 1st entire, multidisciplinary reference overlaying the world of antimicrobial drug resistance in micro organism, fungi, viruses, and parasites from uncomplicated technological know-how, medical, and epidemiological perspectives.
The first quantity, Antimicrobial Drug Resistance, Mechanisms of Drug Resistance, is devoted to the organic foundation of drug resistance and powerful avenues for drug improvement. With the emergence of extra drug-resistant lines, the method of facing the drug resistance challenge needs to comprise the study of other facets of the mechanisms of bacterial resistance and the dissemination of resistance genes in addition to study using new genomic info. those techniques will allow the layout of novel options to strengthen new antibiotics and look after the effectiveness of at present to be had ones.
The moment quantity, Antimicrobial Drug Resistance, medical and Epidemiological Aspects, is dedicated to the medical points of drug resistance. even supposing there's facts that limited use of a selected antibiotic may be by means of a lessen in drug resistance to that agent, drug resistance keep watch over isn't really simply completed. hence, the infectious sickness doctor calls for enter from the scientific microbiologist and an infection keep an eye on professional to make knowledgeable offerings for the powerful therapy of varied lines of drug-resistant pathogens in person patients.
This 2-volume set is a crucial reference for college students in microbiology, infectious illness physicians, scientific scholars, easy scientists, drug improvement researchers, microbiologists, epidemiologists, and public healthiness practitioners.
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Extra info for Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects
Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene 145. 146. 147. 148. 149. 150. 151. 152. 153. 154. 155. 156. 157. 158. 159. 160. 161. 162. encoding dihydropteroate synthase and characterization of the enzyme. J Bacteriol 1987;169:4320–4326 Maskell JP, Sefton AM, Hall LM. Mechanism of sulfonamide resistance in clinical isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother 1997;41:2121–2126 Padayachee T, Klugman KP. Novel expansions of the gene encoding dihydropteroate synthase in trimethoprim–sulfamethoxazoleresistant Streptococcus pneumoniae.
92. 93. in the United States in 1999–2000. Antimicrob Agents Chemother 2005;49:3031–3033 Farrell DJ, Jenkins SG. Distribution across the USA of macrolide resistance and macrolide resistance mechanisms among Streptococcus pneumoniae isolates collected from patients with respiratory tract infections: PROTEKT US 2001–2002. J Antimicrob Chemother 2004;54(Suppl S1):17–22 Clancy J, Petitpas J, Dib Hajj F, et al. Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes.
GAS is a common cause of bacterial infections especially in children of more than 3 years of age, and also in other age groups. g. pharyngitis and impetigo). However, invasion especially from the skin can lead to septicaemia or severe deep-seated tissue infections, such as necrotizing fasciitis and myositis. Other clinical manifestations of GAS include scarlet fever, peritonsillar and retropharyngeal abscesses, otitis media, sinusitis, myositis, lymphangitis, meningitis, suppurative arthritis, endocarditis, osteomyelitis, pneumonia, erysipelas, cellulites, streptococcal toxic shock syndrome, vaginitis, and balanitis (7–10).
Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects by Lesley McGee, Keith P. Klugman (auth.), Douglas L. Mayers MD (eds.)