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Download e-book for kindle: An update on glomerulopathies : clinical and treatment by Sharma S Prabhakar

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By Sharma S Prabhakar

ISBN-10: 9533076739

ISBN-13: 9789533076737

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Extra resources for An update on glomerulopathies : clinical and treatment aspects

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Distinguishing between primary and secondary FSGS is important, since secondary FSGS should not respond to immunosuppressive therapy. Instead, the inciting condition or toxin should be alleviated or stopped in secondary form FSGS if possible. Unfortunately, distinguishing between primary vs. secondary FSGS can be challenging, since focal sclerosis lesions may be present in a diverse assortment of glomerular, vascular, and tubular injuries, just as global sclerosis represents a common endpoint lesion for the end-stage renal disease.

Unfortunately, distinguishing between primary vs. secondary FSGS can be challenging, since focal sclerosis lesions may be present in a diverse assortment of glomerular, vascular, and tubular injuries, just as global sclerosis represents a common endpoint lesion for the end-stage renal disease. 5. Laboratory findings Urine analysis may have wide range of findings starting from fatty casts to dysmorphic red blood cells and red blood cell casts. Proteinuria varies from less than 1 gm to 30g/day. Hypoproteinemia is common in patients with FSGS, with total serum protein reduced to varying extents.

1 Non-immunosuppressive drug treatment Symptomatic relief of edema helps the patient feel better. In most patients, loop diuretics are needed to promote diuresis. Patients with massive edema with impaired oral absorption may require intravenous administration of loop diuretics. In patients with refractory conditions, addition of other diuretics (eg, metolazone) and potassium-sparing agents (eg, spironolactone, triamterene) facilitates diuresis and prevents hypokalemia. Rarely, some patients (especially children) with intractable edema may need intravenous albumin and diuretics in a hospital setting to initiate diuresis.

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An update on glomerulopathies : clinical and treatment aspects by Sharma S Prabhakar


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